Education Experience (教育经历)

• 2008.09-2013.06 Bachelor of Preventive Medicine, School of Public Health, Jilin University

• 2013.09-2016.06 Master of Labor Health and Environmental Health, School of Public Health, Jilin University

• 2016.09-2019.06 Doctor of Labor Health and Environmental Hygiene, School of Public Health, Jilin University

  Working Experience（工作经历）

• 2019.09-present School of Public Health, Jilin University

  Research Fields（研究领域）

• Effects of Environmental Endocrine Disruptors on Human Health

  Research Projects（科研项目）

• Science and Technology Development Program of Jilin Provincial Science and Technology Department, Project No. 20200403113SF, Preparation of apolipoprotein B100 antibody and its application in the diagnosis and treatment of coronary heart disease, 01/2020-122/2020, in research, participating;

• Science and Technology Development Program of Jilin Province Department of Science and Technology, Project No. 20200201081JC, Preparation of self-supplied oxygen polytungstate nanosystem and its effect in radiotherapy sensitization, 01/2020-122/20, in research, participating;

• Education Department Project of Jilin Province,JJKH20201118KJ, The dual regulation mechanism of Notch signaling pathway in lipid metabolism disorders induced by plasticizer DEHP, 01/2020-121/2021, in research, participating.

• Education Department Project of Jilin Province,JJKH20201118KJ, The effect of MEHP on the proliferation and invasion of neuroblastoma cells and its mechanism, 2012/01-2020/12, in progress, participating.

  Publications （学术论文）

• Qi W, Xu Q, Xu Y, Wang Z, Yang L, Guo S, Shi Y, Zhao T, Zhou L, Ye L. Effect of Notch pathway on lipid accumulation induced by mono-2-ethylhexyl phthalate on 3T3-L1 cells [J]. Ecotoxicol Environ Saf. 2021, 208.

• Qi W, Zhou L, Zhao T, Ding S, Xu Q, Han X, Zhao Y, Song X, Zhao T, Zhang Z, Ye L. Effect of the TYK-2/STAT-3 pathway on lipid accumulation induced by mono-2-ethylhexyl phthalate [J]. Molecular and Cellular Endocrinology. 2019. 484: 52-58.

• Qi W, Zhang B, Qi Y, Guo S, Tian R, Sun J, Zhao M. The Anti-Proliferation Activity and Mechanism of Action of K₁₂[V₁₈O₄₂(H₂O)]∙6H₂O on Breast Cancer Cell Lines [J]. Molecules. 2017. 22(9):1535.

• Qi W, Qin Y, Qi Y, Guo L, Li J. In Vitro Antitumor Activity of a Keggin Vanadium-Substituted Polyoxomolybdate and Its ctDNA Binding Properties[J].Journal of Chemistry.2016.753751.

• Qi W, Li X, Xu Q, Yang L, Guo S, Shi Y, Zhao T, Zhou L, Ye L. Effect of Notch Pathway on Lipid Accumulation Induced by DEHP/MEHP in vitro and in vivo. 2019环境与健康会议. 2019.10.28-2019.10.30.

• Shi Y^#, Qi W^#, Xu Q, Wang Z, Cao X, Zhou L, Ye L. The role of epigenetics in the reproductive toxicity of environmental endocrine disruptors [J]. Environ Mol Mutagen. 2021 62(1):78-88.

• Xu Q, Qi W, Zhang Y, Wang Q, Ding S, Han X, Zhao Y, Song X, Zhao T, Zhou L, Ye L. DNA methylation of JAK3/STAT5/PPARγ regulated the changes of lipid levels induced by di (2-ethylhexyl) phthalate and high-fat diet in adolescent rats [J]. Environ Sci Pollut Res Int. 2020,27(24):30232-30242.

• Guo S, Zhang B, Qi W, Cao X, Xu Y, Zhang X, Li X, Zhou L, Ye L. Role of estrogen receptor alpha in MEHP-induced proliferation and invasion of SH-SY5Y cells [J]. Toxicology. 2021,453:152734.

• Han X, Gao Y, Qi W, Ding S, Zhang Y, Xu Q, Zhao Y, Song X, Zhao T, Zhou L, Ye L. Influencing factors of coexistence PreDM and PreHTN in occupational population of state grid corporation of Chinese [J]. Arch Environ Occup Health. 2020;75(6):365-370.

• Ding S, Zhang Z, Chen Y, Qi W, Zhang Y, Xu Q, Liu H, Zhang T, Zhao Y, Han X, Song X, Zhao T, Ye L. Urinary levels of phthalate metabolites and their association with lifestyle behaviors in Chinese adolescents and young adults [J]. Ecotoxicology and Environmental Safety. 2019. 183. 109541.

• Zhang Y, Zhang Z, Zhou L, Zhu J, Zhang X, Qi W, Ding S, Xu Qu, Han X, Zhao Y, Song X, Zhao T, and Ye L. Di (2-ethylhexyl) phthalate Disorders Lipid Metabolism via TYK2/STAT1 and Autophagy in Rats [J]. Biomed Environ Sci. 2019. 32(6): 406-418.

• Zhu J, Zhao Y, Gao Y, Li C, Zhou L, Qi W, Zhang Y, Ye L. Effects of Different Components of PM2.5 on the Expression Levels of NF-κB Family Gene mRNA and Inflammatory Molecules in Human Macrophage [J]. Int J Environ Res Public Health. 2019. 16(8): 1408.

• Han X, Gao Y, Qi W, Ding S, Zhang Y, Xu Q, Zhao Y, Song X, Zhao T, Zhou L, Ye L. Influencing factors of coexistence PreDM and PreHTN in occupational population of state grid corporation of Chinese [J]. Arch Environ Occup Health. 2019. 17: 1-6.

• Zhou L, Zheng D, Song X, Zhu J, Qi W, Ding S, Zhang Y, Xu Q, Han X, Zhao Y, Zhao T, Guo S, Shi Y, Yang L, Ye L. Alternated mRNA expression of the genes in chromosome 9p21 is associated with coronary heart disease and genetic variants in chromosome 9p21 [J]. Thromb Res. 2019. 178:17-19.

• Cao H, Li C, Qi W, Meng X, Tian R, Qi Y, Yang W, Li J. Synthesis, cytotoxicity and antitumour mechanism investigations of polyoxometalate doped silica nanospheres on breast cancer MCF-7 cells [J]. Plos One. 2017. 12(7): e0181018.

• Wang An, Yang Y, Qi Y, Qi W, Fei J, Ma H, Zhao J,Cui W, Li J. Fabrication of Mesoporous Silica Nanoparticle with Well-Defined Multicompartment Structure as Efficient Drug Carrier for Cancer Therapy in Vitro and in Vivo [J]. ACS Applied Materials & Interfaces. 2016. 8(14): 8900-8907.  

• Li C, Qi W , Cao H, Qi Y, Zhang S, Xu S, Sun J, Guo S. BSA-binding properties and anti-proliferative effects of amino acids functionalized polyoxomolybdates [J]. Biomedicine & Pharmacotherapy. 2016. 79: 78-86.

• Liu Z, Qi W, Li C, Qi Y, Li J, Wang E, Yang X. Two pillared-helical-layer frameworks based on spiral chainlike metavanadate and [M(btx)]⁽²⁺⁾ complexes [J]. Journal of Coordination Chemistry. 2015. 68(5): 743-751.

• Chun-yan li, LuChunMei QiYanFei QiWen, Sun Jiaheng, NiuQian. 18 kinds of sex hormones in pilose antler extract technology research [J]. Journal of molecular science. 2016. 32 (02) : 123-128.