EducationExperience

• 2008/09—2010/10 New York University School of Medicine, PhD. joint training

• 2007/09—2011/06 Jilin University, School of Public Health, PhD

• 2005/09—2007/06 Jilin University, School of Public Health, Master

• 1998/09—2003/06 Jilin University, School of Public Health, Bachelor

Working Experience

• 2019/09-presentProfessor, School of Public Health, Jilin University

• 2014/09-2019/09Associate Professor, School of Public Health, Jilin University

• 2011/09—2014/09 Lecturer,School of Public Health, Jilin University,

• 2003/06—2011/09 Teaching Assistant,School of Public Health, Jilin University,

Research Fields

• Nutrition and disease

• Food safety and testing technology research

Research Projects

• Project of Jilin Province Development and Reform Commission, 2020C038-7, Research platform for detection technology of food-borne pathogens, 2020/01-2021/12, in research, lead

• Jilin Province Science and Technology Department Project, 20180101095JC, Research on rapid detection technology of foodborne pathogens based on phage display, biological barcode and other technologies, 2018/01-2020/12, in research, lead

• Project of Jilin Province Health and Family Planning Commission, 2017J074, Research on rapid detection technology of human brucellosis based on paper chip technology, 2018/01-2020/12, in research, lead

• National Natural Science Foundation of China Youth Project, 81502849, Research on rapid enrichment and detection technology of Vibrio parahaemolyticus in food, 2016/01-2018/12, completed, participated

• National Natural Science Foundation of China, 81573184, JAK-STAT signaling pathway advocates the mechanism of DEHP-induced lipid metabolism disorders, 2016/01-2019/12, completed, participated

• National Natural Science Foundation of China Youth Project, 81401721, Research on rapid diagnosis technology of brucellosis, 2015/01-2017/12, completed, chaired

• National Natural Science Foundation of China General Project, 81473018, Research on the simultaneous rapid enrichment and detection technology of three zoonotic infectious pathogens, 2015/01-2018/12, completed, participated

• The project commissioned by the local government, the survey and research on the trace element content of mineral water in Changbai Mountain and the residents' health, 2014/07-2015/07, completed, chaired

• Project of Jilin Provincial Department of Science and Technology, 20130522056JH, Construction of light-controlled drug delivery system and research on anti-tumor effect, 2013/01-2015/12, completed, chaired

• Project of Jilin Province Science and Technology Department, YYZX201123-2, Research on the development and application of polysaccharide mixture health products, 2011/06-2014/06, completed, participated

• Jilin Province World Bank Loan Agricultural Products Quality and Safety Project, 2011-Z59, Research on risk analysis and safety control technology of food contact materials, 2011/01-2014/12, completed, participated

• National Natural Science Foundation of China, 81072337, Preparation of polyacid-based nano-fluorescent biological probes and their application in the immunodetection of zoonotic diseases, 2011/01-2013/12, completed, participated

  Publications

• 1. Jinpeng Wang, Yue Wang, Yuyi Zhao, Jinbin Zhao, Beilin Zhang, Kun Xu*.EGCG Regulates Cell Apoptosis of Human Umbilical Vein Endothelial Cells Grown on 316L Stainless Steel for Stent Implantation. Drug Design, Development and Therapy, 2021:15,493–499.

• 2.Dan Wang, Fengnan Lian, Shuo Yao, Yi Liu, Jinpeng Wang, Xiuling Song, Lirui Ge, Yue Wang, Yuyi Zhao, Jiamei Zhang, Chao Zhao*, Kun, Xu*. Simultaneous Detection of Three Foodborne Pathogens Based on Immunomagnetic Nanoparticles and Fluorescent Quantum Dots. ACS Omega, 2020, 5(36):23070-23080.

• 3.Beilin Zhang, Jinpeng Wang, Qiyan Wei, Yi Liu, Huiwen Zhang, Xiaohui Chen, Kun Xu*. Epigallocatechin-3-O-gallate modulates the diversity of gut microbiota in ovariectomized rats.Food Science & Nutrition, 2020,8(2):1295-1302

• 4.Xinxin Li, Chao Zhao, Yi Liu, Yue Li, Fengnan Lian, Dan Wang, Ying Zhang, Juan Wang, Xiuling Song, Juan Li, Yanming Yang*, Kun Xu*. Fluorescent signal amplification assay for the detection of B. melitensis 16M, based on peptide-mediated magnetic separation technology and AuNPs-mediated bio-barcode assembled by quantum dots technology. Analyst, 2019.2.22, 144:2704-2715.

• 5.Xinxin Li, Xuejing Li, Yuanyuan Guo, Yushen Liu, Shujuan Mei, Xiuling Song, Jinhua Li, Alvin G. Grugbaye, Juan Li, Kun Xu*. Development and Assessment of a Paper-based Enzyme-linked Immunosorbent Assay for the Colorimetric Diagnosis of Human Brucellosis, Analytical letters, 2019.2.8, 50(10):1614-1628.

• 6.Yushen Liu, Juan Wang, Chao Zhao, Xiaoxiao Guo, Xiuling Song, Wei Zhao, Sijie Liu, Kun Xu*, Juan Li*. A multicolorimetric assay for rapid detection of Listeria monocytogenes based on the etching of gold nanorods, An alytica Chimica Acta, 2019.2.07, 1048: 154-160.

• 7.Pang B, Zheng Y, Wang J, Liu Y, Song X, Li J, Yao S, Fu K, Xu K*, Zhao C*, Li J*. Colorimetric detection of Staphylococcus aureus using gold nanorods labeled with yolk immunoglobulin and urease, magnetic beads, and a phenolphthalein impregnated test paper. Microchimica Acta. 2019, 186(9):611. doi: 10.1007/s00604-019-3722-0.

• 8.Xiaocui Li, Yuanyuan Guo, Xiuling Song, Yinghua He, Huiwen Zhang, Hao Bao, Xinxin Li, Yushen Liu, Yue Zhai, Juan Wang, Kun Xu*, Juan Li*. A cross-sectional survey based on blood VOCs, hematological parameters and urine indicators in a population in Jilin, Northeast China. Environ Geochem Health, 2019.1.16, https://doi.org/10.1007/s10653-019-00241-6.1.

• 9.Dehui Yin, Li Li, Xiuling Song, HanLi, Juan Wang, Wen Ju, Xiaofeng Qu, Dandan Song, Yushen Liu, Xiangjun Meng, Hongqian Cao, Weiyi Song, Rizeng Meng, Jinhua Liu, Juan Li*, Kun Xu*. A Novel Multi-Epitope Recombined Protein for Diagnosis of Human Brucellosis[J]. BMC Infectious Diseases, 16(1):219. doi: 10.1186/s12879-016-1552-9.

• 10. Dehui Yin, Li Li, Dandan Song, Yushen Liu, Wen Ju, Xiuling Song, Juan Wang, Bo Pang,Kun Xu*, Juan Li*. A novel recombinant multi-epitope protein against Brucella melitensisinfection. [J]. Immunology Letters 2016, 175: 1-7.

• 11. Wen Ju, Xiuling Song, Gang Yan, Kun Xu, Juan Wang, Dehui Yin, Li Li, Xiaofeng Qu, Yangguang Li*, Juan Li*. Layer-by-Layer Assembly of Polyoxometalate-Pyrene-Decorated Fluorescent Microspheres for Suspension Immunoassay of Listeria Monocytogenes[J]. Journal of material chemistry b , 2016. doi: 10.1039/C6TB00986G.

• 12.Li Li, Ju Wen, Yin Dehui, Meng Rizeng, Li Juan, Song Xiuling, Xu Kun*. Preparation of Biotin-labeled Brucella Polyclonal Antibody[J]. Chinese Journal of Biologicals, 2015,（02): 147 ~150+154.

• 13. Juan Wang., Xiaofeng Qu., Yanfei Qi, Jinhua Li, Xiuling Song, Li Li, Dehui Yin, Kun Xu*, Juan Li*. Pharmacokinetics of Anti-HBV Polyoxometalate in Rats[J]. PLOS ONE, 2014, 9(6):e98292.

• 14. Juan Wang, Yang Liu,Kun Xu, Yanfei Qi,Jun Zhong, Kai Zhang, Juan Li*, Enbo Wang,Ziyu Wu, and Zhenhui Kang*. Broad-spectrum antiviral property of polyoxometalate localized on a cell surface[J]. ACS Appl Mater Interfaces, 2014, 6(12):9785-9.

• 15. Ming Ren, Lingyan Ye, Xiaoshi Hao, Zhixing Ren, Shuping Ren, Kun Xu, Juan Li. Polysaccharides from Tricholoma matsutake and Lentinus edodes enhance 5-fluorouracil-mediated H22 cell growth inhibition[J]. J Tradit Chin Med, 2014, 34(3): 309-316.

• 16. Ye Lingyan, Ren Ming, Lu Lin, Li Li, Qi Yanfei, Li Juan, Xu Kun*. Preparation of polysaccharide mixture and indirect anti-tumor activity in vitro[J]. Journal of Jilin University (Medical Edition), 2014, (05):033~ 1037.

• 17. Ren Ming, Hao Xiaoshi, Ye Lingyan, Zhang Wanze, Qi Yanfei, Xu Kun, Li Juan. Extraction and isolation of ginseng polysaccharide and its anti-tumor effect in vitro[J]. Journal of Jilin University (Medical Edition), 2014, (04): 812~815.

• 18. Yao Yao, Zhang Maomao, Li Li, Yin Dehui, Qu Xiaofeng, Qi Yanfei, Li Juan, Xu Kun*.. Anti-influenza A virus effect and toxicity evaluation of a new type of hand sanitizer containing polyacid compounds[J].Journal of Jilin University (Medical Sciences) Edition), 2014, (01): 121~125.

• 19.Yan-Fei Qi*, Kun Xu, Li-Jun Lu, Juan Li* and En-Bo Wang. Self-assembly of a 3-D self-catenated framework based on [V4O12]4- polyoxoanions and cobalt-organic polymer[J]. 2013, 66(7)：1228-1237.

• 20. Xiu-ling Song, Bo Li, Kun Xu, Juan Liu, Wen Ju, Juan Wang, Xiao-dong Liu, Juan Li* and Yan-fei Qi *. Cytotoxicity of water-soluble mPEG-SH-coated silver nanoparticles in HL-7702 cells[J]. Cell Biology and Toxicology, 2012, 28(4):225-237.

• 21. Kun Xu, Xinyu Wu., Ellen Shapiro, Honging Huang, Lixia Zhang, Duane Hickling, Yan Deng,Peng Lee, Juan Li, Herbert Lepor, Irina Grishina*. Bmp7 Functions via a Polarity Mechanism to Promote Cloacal Septation[J]. PLoS ONE,2012, 7(1):e29372.

• 22. Meng Fan-xu , Xu Hua-ping , Qi Yan-fei , Xu Kun , Song Xiu-ling , Niu Shu and Li Juan*. Preliminary Studies on X-Ray-sensitive Liposome[J]. Chem. Res. Chinese Universities, 2012, 28(2), 319-322.

• 23. Yanfei Qi; Hong Zhang; Juan Wang; Yanfang Jiang; Jinhua Li; Ye Yuan; Shiyao Zhang;；Kun Xu; Yangguang Li; Juan Li*; Junqi Niu*; Enbo Wang. In vitro anti-hepatitis B and SARS virus activities of a titanium-substituted-heteropolytungstate[J]. Antiviral Research, 2012, 93(1):118-125.

• 24. Yuan Ye, Li Jinhua, Wang Juan, Zhang Shiyao, Ju Wen, Qi Yanfei, Li Juan, Xu Kun*. Toxicological safety evaluation of a new polyacid compound NCW-6[J]. Journal of Jilin University (Medical Edition), 2012, 38 ( 1): 28~32.

• 25. Wu Xinyu#, Xu Kun#, Zhang Lixia, Deng Yan, Lee Peng, Shapiro Ellen, Monaco Marie, Makarenkova Helen P, Li Juan, Lepor Herbert, Grishina Irina. Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism[J]. Developmental Biology, 2011, 356（2）:337~349.

• 26. Wu Xinyu, Daniels Garrett, Shapiro Ellen, Huang Hongying, Xu Kun, Li Yirong, Logan Susan, Greco M. Alba, Peng Yi, Monaco Marie E, Melamed Jonathan, Lepor Herbert, Grishina Irina, Lee Peng. LEF1 Identifies Androgen-Independent Epithelium in the Developing Prostate[J]. Molecular Endocrinology，2011, 25（6）:1018~1026.

• 27. Preparation and application of a brucellosis-specific fusion protein antigen, application publication number: CN105906714A

• 28. Preparation and application of Brucella multi-epitope fusion protein vaccine, application publication number: CN105906717A

• 29.Anti-radiation and auxiliary anti-tumor drugs and applications, authorization number: ZL201310600627.6

• 30. Rare earth heteropoly compound antiviral drugs, authorization number: ZL2006 10016659.1