Education Experience

l 2000-2003, Ph.D. Radiobiology, Jilin University

l 1993-1996, M.Sc. Toxicology, Norman Bethune University of Medical Sciences

l 1988-1993, B.Sc. Preventive medicine, Norman Bethune University of Medical Sciences

Working Experience

l 2009-present, Professor, Jilin University, Department of Nutrition and Food Science

l 2007-2008,  Visiting scholar, Child & Family Research Institute at University of British Columbia, Canada

l 2000-2001, Visiting scholar, Department of Microbiology at National Institute of Brewing, Japan

Research Fields

• Nutrition and Health

• Molecular nutriology of disease

• Maternal and infants nutrition

Research Projects

• ABBOTT NUTRTION R&D, Study on level of total potentially available nucleosides and rhythm change of relative nutrients level in Chinese breast milk, 2020-06-2022-05

• Health Commission of Jilin province, 2019J027, Study on dynamic change of nutrients in breast milk for preterm and term infants and its influence on growth development of infants, 2020-01-2021-12

• ABBOTT NUTRTION R&D, 2019YX078，Study on level of total potentially available nucleosides in Chinese breast milk, 2019-01-2020-12

• ABBOTT NUTRTION R&D, Study on level of nucleotides in Chinese breast milk, 2018-01-2019-12

• Educational Department of Jilin province, JJKH20170875KJ，Study on the effect of diet and Elovl gene variation interaction on the composition of fatty acids in milk, 2017-01-2018-12

• Health and Family Planning Commission of Jilin Province, 2016J077, Study on the relationships between diet pattern of lactating mothers and fatty acid profile in breast milk, 2017-01-2018-12

• Jilin Aodong Jiaosu Technology Co. Ltd.，Study on biological function of Aodong fermented beverage, 2016-04-2019-04

• National Natural Science Foundation of China, 81102115, Study on the effect of dietary fatty acids and FADS gene polymorphism on levels of polyunsaturated fatty acids in milk and infant intelligence, 2012-01-2014-12

Publications

• Wang Bing; Dong Hanyu; Feng Junyan; Li Honghua; Zhang Yu; Jia Feiyong^*; Xie Lin^*; Retrospective analysis of the correlation between serum vitamin D levels and blood amino acids levels in children with autism: Exploration of possible mechanisms of the effect of vitamin D on autism, Research in Autism Spectrum Disorders, 2021, 80. (IF= 1.688)

• Yan Wang, Yiwei Tang, Ye Ji, Wenhui Xu, Naeem Ullah, Haitao Yu, Yixia Wu, Lin Xie^*. Association between FADS1 rs174547 and levels of long-chain PUFA: a meta-analysis，British Journal of Nutrition，2020，doi:10.1017/S0007114520005103 (IF=3.334)

• Wu Y, Wang Y, Tian H, Lu T, Yu M, Xu W, Liu G, Xie L^*. DHA intake interacts with ELOVL2 and ELOVL5 genetic variants to influence polyunsaturated fatty acids in human milk. Journal of Lipid Research, 2019, 60(5): 1043-1049. (IF=4.734)）

• Tian HM, Wu YX, Lin YQ, Chen XY, Yu M, Lu T, Xie L^*. Dietary patterns affect maternal macronutrient intake levels and the fatty acid profile of breast milk in lactating Chinese mothers. Nutrition, 2019, 58: 83-88. (IF=3.591)）

• Wang, Yan; Yu, Miao; Shi, Yongwei; Lu, Tong; Xu, Wenhui; Sun, Yaqiong; Yang, Lutong; Gan, Zhenwei; Xie, Lin^*; Effects of a Fermented Beverage of Changbai Mountain Fruit and Vegetables on the Composition of Gut Microbiota in Mice, Plant Foods for Human Nutrition, 2019, 74(4): 468-473. (IF= 2.901)

• LI Xiang, GAN Zhen Wei, DING Zhen, WU Yi Xia, CHEN Xue Yan,TIAN Hui Min, LIU Guo Liang, YANG Ye Tong, and XIE Lin^*, Genetic Variants in the ELOVL5 but not ELOVL2 Gene Associated with Polyunsaturated Fatty Acids in Han Chinese Breast Milk, Biomed Environ Sci, 2017; 30(1): 64-67. (IF=2.518)  

• Yixia Wu;   Lixin Zeng;   Xueyan Chen;   Yang Xu;   Lin Ye;   Ling Qin;   Liping Chen;   Lin Xie*, Association of the FADS gene cluster with coronary artery disease andplasma lipid concentrations in the northern Chinese Han population, Prostaglandins, Leukotrienes and Essential Fatty Acids, 2017,117:11-16. (IF=2.864)）

• Guoliang Liu^#, Zhen Ding^#, Xiang Li, Xueyan Chen, Yixia Wu, Lin Xie^*. Relationship between polyunsaturated fatty acid levels in maternal diets and human milk in the first month post-partum, Journal of Human Nutrition and Dietetics, 2016, 29(4): 405-410. (IF=3.088)）

• Zhen Ding, Guoliang Liu, Xiang Li, Xueyan Chen, Yixia Wu, Cancan Cui, Xi Zhang, Guang Yang, Lin Xie^*. Association of polyunsaturated fatty acids in breast milk with fatty acid desaturase gene polymorphisms among Chinese lactating mothers. Prostaglandins, Leukotrienes and Essential Fatty Acids, 2016, 109: 66-71. (IF=2.864)）

• Juan Deng^#, Xiang Li^#, Zhen Ding, Yixia Wu, Xueyan Chen, Lin Xie^*. Effect of DHA supplements during pregnancy on the concentration of PUFA in breast milk of Chinese lactating mothers. Journal of Perinatal Medicine, 2017, 45(4): 437-441. (IF=1.361)）

• Lin Xie, Sheila M. Innis^*. Genetic variants of the FADS1 FADS2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation. Journal of Nutrition, 2008, 138(11): 2222-2228. (IF=4.416)