Education Experience (教育经历)

2005.9-2009.6         Ph.D. in Radiobiology and Oncology, School of Public     Health, Jilin University, Changchun, China                     Supervisor: Shouliang Gong, M.D., Ph.D.

2003.9-2005.6         Master Degree in Radiobiology, School of Public Health,

Jilin University, Changchun, China

Supervisor: Shouliang Gong, M.D., Ph.D.

1996.9-2001.6         Bachelor of Preventive Medicine

School of Public Health, Jilin University, Jilin, China

Working Experience（工作经历）

• 2014.10 – present  assistant professor, Department of Radiobiology,

• 2006.9 - 2014.9  Lecturer, Department of Radiobiology,

School of Public Health, Jilin University, Changchun, China

• 2001.7 - 2006.9 Assistant, Department of Radiobiology,

  School of Public Health, Jilin University, Changchun, China

Research Fields（研究领域）

• Radiation Oncology

• radiobiological effects

Research Projects（科研项目）

• Science and Technology Development Plan of Jilin (20180101305JC)，Roles and mechanisms of mitochondrial targeting photosensitizer on radiosensitization in tumor cells

• National Nature Science Foundation of China（31600678）, The effects and molecular mechanisms of p53 regulates LOX in the radioresistance of tumor cells

• Bethune Project of Jilin University (2020B06), Roles and mechanisms of ATRX regulating radiation-induced apoptosis through MDM2/p53 pathway.

Publications （学术论文）

• Li Xin#; Fang Fang#; Gao Ying; Tang Geng; Xu Weiqiang; Wang Yihan; Kong Ruoxian; Tuyihong Ayixianguli; Wang Zhicheng*; ROS Induced by KillerRed Targeting Mitochondria (mtKR) Enhances Apoptosis Caused by Radiation via Cyt c/Caspase-3 Pathway , Oxidative Medicine and Cellular Longevity, 2019, 2019.

• Yu Lei; Fang Fang; Lu Shuangchen; Li Xin; Yang Yanming*; Wang Zhicheng*; lncRNA-HIT promotes cell proliferation of non-small cell lung cancer by association with E2F1 , Cancer Gene Therapy, 2017, 24(5): 221-226.

• Song Xiangfu; Ren Ting; Zheng Zhou; Lu Tiancheng; Wang Zhicheng*; Du Fengguo*; Tong Haibin*; Anti-tumor and immunomodulatory activities induced by an alkali-extracted polysaccharide BCAP-1 from Bupleurum chinense via NF-kappa B signaling pathway , International Journal of Biological Macromolecules, 2017, 95: 357-362.

• Yang Yan Ming; Fang Fang; Li Xin; Yu Lei*; Wang Zhi Cheng*; TRAIL overexpression co-regulated by Egr I and HRE enhances radiosensitivity of hypoxic A549 cells depending on its apoptosis inducing role , Oncology Reports , 2017, 37(1): 533-539.

• Jianfeng Wang#; Yana Li#; Yang Liu; Yanbo Li; Shouliang Gong; Fang Fang* ; Zhicheng Wang*; Overexpression of truncated AIF regulated by Egr1 promoter radiation-induced apoptosis on MCF-7 cells, Radiat Environ Biophys, 2015, 54(4) : 413-421.